Publications including the Master’s Thesis work of MBCM alumni.
2021
Gut-adipose tissue crosstalk: A bridge to novel therapeutic targets in metabolic syndrome? Article. |
Auxin-degron system identifies immediate mechanisms of OCT4. Article. |
2020
Sex differences in offspring neurodevelopment, cognitive performance and microglia morphology associated with maternal diabetes: Putative targets for insulin therapy. Article. |
Social subordination induced by early life adversity rewires inhibitory control of the prefrontal cortex via enhanced Npy1r signaling. Article. |
Comparison of size distribution and (Pro249-Ser258) epitope exposure in in vitro and in vivo derived Tau fibrils. Article. |
Microglia cytoarchitecture in the brain of adenosine A 2A receptor knockout mice: Brain region and sex specificities. Article. |
Induction of apoptosis increases sensitivity to detect cancer mutations in plasma. Article. |
An Overview of Antiretroviral Agents for Treating HIV Infection in Paediatric Population. Article. |
Understanding the Binding Specificity of G-Protein Coupled Receptors toward G-Proteins and Arrestins: Application to the Dopamine Receptor Family. Article. |
2019
Mimicking Age-Associated Gadd45γ Dysregulation Results in Memory Impairments in Young Adult Mice. Article. |
Mitochondrial fission requires DRP1 but not dynamins. Article. |
The bystander effect contributes to the accumulation of senescent cells in vivo. Article. |
Abnormal mGluR-mediated synaptic plasticity and autism-like behaviours in Gprasp2 mutant mice. Article. |
2018
FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence. Article. |
Nutrient limitation affects presynaptic structures through dissociable Bassoon autophagic degradation and impaired vesicle release. Article. |
Medial Frontal Lobe Neurochemistry in Autism Spectrum Disorder is Marked by Reduced N-Acetylaspartate and Unchanged Gamma-Aminobutyric Acid and Glutamate + Glutamine Levels. Article. |
PROneurotrophins and CONSequences. Article. |
Astroglial CB1Receptors Determine Synstroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory. Article. |
Toxicity of lupane derivatives on anionic membrane models, isolated rat mitochondria and selected human cell lines: Role of terminal alkyl chains. Article. |
Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing. Article. |
A Microfluidic Culture Platform for Neurotrophin Signaling Studies. Article. |
Computational Tools for the Structural Characterization of Proteins and Their Complexes from Sequence‐Evolutionary Data. Article. |
In Silico Studies Targeting G-protein Coupled Receptors for Drug Research Against Parkinson’s Disease. Article. |
Computational Approaches in Antibody-drug Conjugate Optimization for Targeted Cancer Therapy. Article. |
2017
The RNA-Binding Protein hnRNP K Mediates the Effect of BDNF on Dendritic mRNA Metabolism and Regulates Synaptic NMDA Receptors in Hippocampal Neurons. Article. |
Spoton: A Machine-Learning Approach for Hot-Spot Determination. Article. |
High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors. Article. |
Mitochondria in Excitatory and Inhibitory Synapses have Similar Susceptibility to Amyloid-β Peptides Modeling Alzheimer’s Disease. Article. |
SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots. Article. |
Computational studies of G protein-coupled receptor complexes: Structure and dynamics. Article. |
Membrane proteins structures: A review on computational modeling tools. Article. |
2016
Inhibitory Injury Signaling Represses Axon Regeneration After Dorsal Root Injury. Article. |
Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models. Article. |
2015
Ischaemia-induced autophagy leads to degradation of gap junction protein connexin43 in cardiomyocytes. Article. |
OXPHOS dysfunction regulates integrin-β1 modifications and enhances cell motility and migration. Article. |
Oxidative stress involving changes in Nrf2 and ER stress in early stages of Alzheimer’s disease. Article. |
Senescent bronchial fibroblasts induced to senescence by Cr(VI) promote epithelial-mesenchymal transition when co-cultured with bronchial epithelial cells in the presence of Cr(VI). Article. |
LRRK2 functions in synaptic vesicle endocytosis through a kinase-dependent mechanism. Article. |
Heart ischemia results in connexin43 ubiquitination localized at the intercalated discs. Article. |
GluN2B-Containing NMDA Receptors Regulate AMPA Receptor Traffic through Anchoring of the Synaptic Proteasome. Article. |
2014
Role of methamphetamine on glioblastoma cytotoxicity induced by doxorubicin and methotrexate. Article. |
Pharmacological profile of brain-derived neurotrophic factor (BDNF) splice variant translation using a novel drug screening assay: a “quantitative code”. Article. |
Stimulation of neural stem cell proliferation by inhibition of phosphodiesterase 5. Article. |
Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus. Article. |
Neurotensin Decreases the Proinflammatory Status of Human Skin Fibroblasts and Increases Epidermal Growth Factor Expression. Article. |
Low amounts of mitochondrial reactive oxygen species define human sperm quality. Article. |
Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation. Article. |
Mitochondrial apoptosis-inducing factor is involved in doxorubicin-induced toxicity on H9c2 cardiomyoblasts. Article. |
2013
Impact of PLK-1 silencing on endothelial cells and cancer cells of diverse histological origin. Article. |
Methylglyoxal further impairs adipose tissue metabolism after partial decrease of blood supply. Arch Physiol Biochem. Article. |
2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: photosensitization efficiency, subcellular localization and in vivo studies. Article. |
Advanced glycation end products and diabetic nephropathy: a comparative study using diabetic and normal rats with methylglyoxal-induced glycation. Article. |
Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin. Article. |
Impaired transcription in Alzheimer’s disease: key role in mitochondrial dysfunction and oxidative stress. Article. |
Neurotensin modulates the migratory and inflammatory response of macrophages under hyperglycemic conditions. Article. |
Dioxin-induced acute cardiac mitochondrial oxidative damage and increased activity of ATP-sensitive potassium channels in Wistar rats. Article. |
2012
CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment. Article. |
Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures. Article. |
Contactin-associated protein 1 (Caspr1) regulates the traffic and synaptic content of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors. Article. |
Acute effects of TCDD administration: special emphasis on testicular and sperm mitochondrial function. Article. |
2011
Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway. Article. |
Differential effects of p,p’-DDE on testis and liver mitochondria: implications for reproductive toxicology. Article. |
Neurotensin downregulates the pro-inflammatory properties of skin-dendritic cells and increases epidermal growth factor expression. Article. |
2010
Biochemical characterization of the maltokinase from Mycobacterium bovis BCG. Article. |
Beneficial effects of dietary restriction in type 2 diabetic rats: the role of adipokines on inflammation and insulin resistance. Article. |
Role of neuropeptides in skin inflammation and its involvement in diabetic wound healing. Article. |